US government, allies publish guidance on how to safely deploy AI agents
Cybersecurity agencies from the United States, Australia, Canada, New Zealand and the United Kingdom jointly published guidance Friday urging organizations to treat autonomous artificial intelligence systems as a core cybersecurity concern, warning that the technology is already being deployed in critical infrastructure and defense sectors with insufficient safeguards.
The guidance focuses on agentic AI — software built on large language models that can plan, make decisions and take actions autonomously. In order for this software to function it needs to connect to external tools, databases, memory stores and automated workflows, allowing it to execute multi-step tasks without human review at each stage.
The guidance was co-authored by the U.S. Cybersecurity and Infrastructure Security Agency, the National Security Agency, the Australian Signals Directorate’s Australian Cyber Security Centre, the Canadian Centre for Cyber Security, New Zealand’s National Cyber Security Centre and the United Kingdom’s National Cyber Security Centre.
The agencies’ central message is that agentic AI does not require an entirely new security discipline. Organizations should fold these systems into the cybersecurity frameworks and governance structures they already maintain, applying established principles such as zero trust, defense-in-depth and least-privilege access.
The document identifies five broad categories of risk. The first is privilege: When agents are granted too much access, a single compromise can cause far more damage than a typical software vulnerability. The second covers design and configuration flaws, where poor setup creates security gaps before a system even goes live.
The third category covers behavioral risks, or cases where an agent pursues a goal in ways its designers never intended or predicted. The fourth is structural risk, where interconnected networks of agents can trigger failures that spread across an organization’s systems.
The fifth category is accountability. Agentic systems make decisions through processes that are difficult to inspect and generate logs that are hard to parse, making it difficult to trace what went wrong and why. The agencies also note that when these systems fail, the consequences can be concrete: altered files, changed access controls and deleted audit trails.
The guidance also flags prompt injection, where instructions embedded inside data can hijack an agent’s behavior to perform malicious tasks. Prompt injection has been a lingering problem with large language models, with some companies admitting that the problem may never be solved.
Identity management gets significant attention throughout the document. The agencies recommend that each agent carry a verified, cryptographically secured identity, use short-lived credentials and encrypt all communications with other agents and services. For high-impact actions, a human should have to sign off, and the guidance is explicit that deciding which actions require that approval is a job for system designers, not the agent.
The agencies admit the security field has not fully caught up with agentic AI. Some risks unique to these systems are not yet covered by existing frameworks, and the guidance calls for more research and collaboration as the technology takes on a growing number of operational roles.
“Until security practices, evaluation methods and standards mature, organisations should assume that agentic AI systems may behave unexpectedly and plan deployments accordingly, prioritising resilience, reversibility and risk containment over efficiency gains,” the guidance reads.
You can read the full guidance below.
